The problem of sepsis in children, the relevance of diagnosis and treatment

Silvija Petuchauskaitė1, 2, Virginija Žilinskaitė1, 3

1Vilnius University, Faculty of Medicine, Vilnius, Lithuania

2Vilnius University, Faculty of Medicine, Clinic of Children ‘s Diseases – Institute of Clinical Medicine, Vilnius, Lithuania

3Vilnius university Hospital Santaros Klinikos, Pediatric Emergency – Intensive care and Anaesthesiology CenterPediatric Intensive Care Unit, Vilnius, Lithuania


Backgroundand aim. Despite medical advances and the rapid development of diagnostic and treatment methods, the problem of paediatric sepsis is still relevant. The problem of sepsis also remains relevant because of changing etiologic factors related to the introduction of new vaccines, the global antimicrobial resistance, and the rise of new resistant strains of microorganisms. The relevance of the sepsis problem is also related to the complicated early suspicion of sepsis, diagnosis, and emergency response. It is medically proven that the outcome of sepsis directly depends on early diagnosis and the proper treatment in the first hour. review aim is to analyse the sepsis problem in children and present the early diagnosis and treatment guidelines.

Materials and methods. The most recent scientific literature was reviewed on paediatric sepsis prevalence, early diagnosis and treatment.

Results. Sepsis is still one of the most common causes of death in children today. The definition of sepsis is still evolving, and it is difficult to accurately understand the epidemiologic situation and the changing aetiology of sepsis in children. The most important factor that can determine a good outcome is the early treatment of sepsis.

Conclusion. Sepsis in children remains one of the greatest burdens on healthcare systems worldwide. Much research is needed to better understand the problem of sepsis. A good outcome of the disease can only be expected if sepsis in children is diagnosed and treated in a timely manner.

Keywords: pediatric sepsis, sepsis early diagnostic, sepsis early management, paediatric sepsis outcomes.

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