Pathophysiology, electrocardiogram morphology and treatment peculiarities of idiopathic ventricular fibrillation

Vaida Punytė1, Gabrielė Čėsnaitė1, Karolina Slapšytė1

1Lithuania University of Health Sciences, Faculty of Medicine


Idiopathic ventricular fibrillation (IVF) is a major unexplained case of sudden cardiac disease, especially in young patients under 35 years of age (approximately 6.8%, up to 35% of cases of sudden death in unexplained patients 18 to 35 years of age). Likely causal mutation in up to 27% of unexplained sudden deaths in children and young adults. Recent studies suggest that a significant subset of IVFs, as defined by extensive investigators, do indeed show subclinical structural changes. These local myocardial lesions are small in size and most detectable in the epicardium. As diagnosed patients, therapeutic episodes of ventricular fibrillation (VF) should be determined by structural or metabolic studies. Generally, primary and secondary prevention of heart failure (HF) is a popular recommendation for implantable cardioverter defibrillator (ICD) one-third of patients with IVF have a recurrence of VF within 5 years of diagnosis determination. VF ablation was recommended if recurrence of VF was not required and the number of complications of ICD was reduced. An example of imaging studies, echocardiography, an association with myocardial scar from idiopathic ventricular arrhythmias (IVA) with the help of cardiac magnetic resonance imaging. IVAs are local, all endocardial but epicardial, treated catheter ablation. IVAs usually result from specific anatomical structures and have characteristic features of the electrocardiogram according to their anatomical background. IVAs are essentially benign, but require medical attention or catheter ablation when IVA is a symptom of IVA or left ventricular dysfunction.

Keywords: idiopathic ventricular fibrillation, ablation, Purkinje, premature ventricular contraction, electrocardiogram, ventricular tachycardia, ventricular arrhythmias.