Intravenous leiomyomatosis. Case report

Diana Žilovič1,2,3, Dovilė Čerkauskaitė 4, Kotryna Kvitkovskaja4, Rūta Čiurlienė3

1 Institute of Biosciences, Life Sciences Center, Vilnius University, Saulėtekio Avenue 7, LT-10222 Vilnius, Lithuania;

2 Laboratory of Clinical Oncology, National Cancer Institute, Santariškių 1, LT-08406 Vilnius Lithuania;

3 Oncogynecology Department, National Cancer Institute, Santariškių 1, LT-08406 Vilnius Lithuania;

4 Lithuanian University of Health Sciences, Faculty of Medicine, Vilnius Lithuania;



Uterine leiomyoma is a very frequent pathology, which affects up to 30% of female population over the age of 35. Although leiomyomas are benign tumors there are some unusual locations and growth patterns of how they can develop and progress. Intravenous leiomyomatosis is one of the extra uterine types of leiomyoma, which is described as intralumenal growth of smooth muscle into either venous or lymphatic vessels outside the limits of myoma. Intravenous leiomyomatosis is a rare benign tumor, but despite its benign histological features, invasion of large vessels and cardiac extension can occur and be fatal (1-3). We present a case of 46-year-old woman who was histologically diagnosed with uterine leiomyoma after vaginal hysterectomy. The aim of the study is to investigate all possible treatments of the intravenous leiomyomatosis and determine the further follow-up

Keywords: intravenous leiomyomatosis, uterine leimyoma.