COVID – 19 related multisystem inflammatory syndrome in children: a literature review

Ieva Balčiūnaitė1, Iveta Tiepelytė1, Vaiva Gudžiūnaitė 1

1Lithuanian University of Health Sciences, Medical Academy, Faculty of Medicine 


Background. In a short time, highly contagious SARS-CoV-2 virus has caused a global pandemic. Although, COVID – 19 infection in children is usually mild or asymptomatic, there are reports about syndrome which occurring within a few weeks of the onset of the infection, causing a life-threatening condition and long-term consequences. The symptoms of this disease are fever, inflammation, gastrointestinal symptoms and dysfunction of many organs.  

Aim: to evaluate clinical features, diagnostic and treatment options of multisystem inflammatory syndrome in children.

Methods: the review of the literature was conducted using the “Pubmed” database. The literature research was conducted using predetermined keywords related with multisystem inflammatory syndrome. More than 30 publications were analyzed.

Discussion. With the emergence of increasingly different strains of SARS-CoV-2 coronavirus, which are becoming more common in children, it is necessary to pay attention to the consequences of infection and emergence of multisystemic inflammatory syndrome. Although MIS-C cases is relatively rare, it is important to further investigate clinical symptoms, diagnostic options, treatment and prevention of multisystem inflammatory syndrome in children because of this syndrome ability to cause the life – threatening conditions and death.

Keywords: multisystem inflammatory syndrome, COVID-19 in children, diagnostics, treatment.