Tautvydas Rugelis1, Agnė Markevičiūtė1, Viktorija Černulytė1

1 Faculty of Medicine, Academy of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania


Introduction: Psoriasis is a chronic disease that is associated with various co-morbidities, including cardiovascular diseases. Psoriasis affects both physical and psychosocial functions of the patients and decreases their quality of life. Depression plays an important role not only in promoting vascular changes, but also in the presence of a risk factor for the development of cardiovascular disease in the presence of psoriasis.

Aim: To perform the analysis of recent publications and to evaluate the relationship between psoriasis, cardiovascular diseases and mental disorders.


  1. Evaluate the relationship between risk factors for psoriasis and other cardiovascular diseases.
  2. To evaluate the importance of psoriasis in patients with cardiovascular diseases.
  3. To evaluate the importance of mental health for diseases of the cardiovascular system in the presence of psoriasis.

Methods: A review of the articles published from 2010 to 2018. Search in the “PubMed” database was performed using search keywords: psoriasis, psoriasis risk factor, psoriasis cardiovascular pathology, psoriasis cardiology, psoriasis and depression, mental disorders in psoriasis. A review and analysis of 37 publications were performed.

Results and conclusions:

  1. The analysed articles demonstrate that in patients with psoriasis, the risk of developing cardiovascular diseases increases with the older age, longer duration of the disease. Also, a significant relationship between psoriasis and obesity, metabolic syndrome, and dyslipidemia.
  2. In patients with psoriasis, there is an increased risk of arterial hypertension and myocardial infarction; the severity of psoriasis is directly related to worse outcomes of cardiovascular diseases.
  3. There is a significant relationship between the occurrence of depression and cardiovascular diseases occurring in patients with psoriasis.