Tumor-induced osteomalacia: nasal cavity phosphaturic mesenchymal tumor a case report and radiologic review

Augustinas Bielinis1, Ruta Kliokyte1, Renata Komiagiene1, Algirdas Edvardas Tamosiunas1

1 Centre of Radiology and Nuclear Medicine, Vilnius University Hospital Santara Clinics, Santariškių g. 2, Vilnius, Lithuania


Background and aim: Phosphaturic mesenchymal tumor is a rare neoplasm composed of bone and soft tissue that is the most common cause of tumor-induced osteomalacia. Due to its nonspecific clinical presentation, rare occurrence and variable features on imaging, diagnosis is often delayed. Our aim is to review this rare disease and it’s diagnostic imaging.

Case presentation: We present a case of a 44-year-old male who presented with osteomalacia-related symptoms and was found to have a nasal cavity mass expressing somatostatin receptors.

Conclusion: Functioning imaging plays a key role in localization of this rare entity with conventional imaging such as computed tomography and magnetic resonance imaging useful in pre-surgery planning.


Keywords: phosphaturic mesenchymal tumor, tumor induced osteomalacia, octreoscan, bone scan.