Daniella Meytin¹

¹Lithuanian University of Health Sciences, Academy of Medicine, Faculty of Medicine 

Abstract

PCOS is the most common endocrine disorder amongst women of reproductive age.  The treatment of one of the possible PCOS complications – infertility – is individual for each patient and couple. Infertility treatment should be started by non-pharmacological means (diet, physical activity), aiming for a weight loss. If this does not help, a pharmacological treatment with clomiphene citrate, letrozole or gonadotropins is induced. Secondary treatment – laparoscopy (invasive procedure). Tertiary treatment – IVF. In all cases, if the patient has a BMI of 25 or more, additional pharmacological treatment with metformin may be given.

Aim: to determine the peculiarities of infertility treatment in patients with polycystic ovary syndrome (PCOS).

Methods: a systematic review of the literature was performed using the PubMed medical database. Selected articles examining the infertility treatment options for PCOS patients. English word combinations were used for search: polycystic ovary syndrome, PCOS, polycystic ovary syndrome infertility, PCOS infertility treatment.

Conclusions. Infertility treatment should be started by non-pharmacological means (diet, physical activity), aiming for a weight loss. If this does not help, a pharmacological treatment with clomiphene citrate, letrozole or gonadotropins is induced. Secondary treatment – laparoscopy (invasive procedure). Tertiary treatment – IVF. In all cases, if the patient has a BMI of 25 or more, additional pharmacological treatment with metformin may be given.

Keywords: polycystic ovary syndrome, PCOS, polycystic ovary syndrome infertility, PCOS infertility treatment.