EARLY DIAGNOSTIC FEATURES OF KIDNEY CANCER
Dr. Lilija Butkevičienė1, Rasita Zamblauskaitė1, Žilvinas Pavilionis2
Lithuanian University of Health Sciences, Radiology clinics.
Objective: To evaluate clinical symptoms and early diagnostic capabilities of kidney cancer.
Material and Methods: A retrospective study was performed. The study was focused on 116 patients treated in LUHS Kaunas Oncology Hospital. All patients were treated for first time diagnosed kidney cancer (screening criteria) in period from 2009 to 2012. The patients undergo surgery and the diagnosis was confirmed histologically. US, CT and clinical symptoms were analyzed. Quantitative data was performed in percent. The qualitative data was performed using SPSS v17 and Microsoft Excel programs. Statistical tests: Chi-test, Student’s t test were used for qualitive data outcomes. Statistical confidence level when p<0,05.
Results: 60 (51,7%) females and 56 (48,3%) males formed main group. Highest morbidity of kidney cancer – in 50-80 year age group, p=0,002. 93 (80%) patients were diagnosed I-II stage kidney cancer, p=0,045. The most common morphological form of the tumor was clear cell renal carcinoma, 111 patients (96%). The most common clinical symptom was pain in the lumbar area, 70 patients (60%). US and CT analysis showed that 112 patients (96,6%) had heterogeneous density tumor. Overgrowth of the adjacent structures were in: US – 10 (8.6%), CT – 32 patients (27,6%), v.cava inferior thrombosis: US – 8 (6,9%), CT – 9 patients (7,7%), kidney gate lymphadenopathy: US – 9 (7,7%), CT – 15 patients (13%). The mean size of node by US – 6,376±3,136cm, by CT – 6,609±3,171cm, p=0,004.
Conclusions: Highest morbidity of kidney cancer – in 50-80 year age group, p=0,002. The most common clinical symptom was pain in the lumbar area, micro-macrohematuria, anemia. The mean size of node by US and CT was with no significant statistical difference, p=0,004. Diagnostic value of tumor outspread by CT study is higher, p<0,001. Most of the kidney tumors were diagnosed in I-II stage – 93 (80%), p=0,045.
KeyWords: Kidney Cancer, Ultrasonography (US), Computed Tomography (CT), Hystology.